眼科

Limoli et al
Oncotarget 2016

RegenKit

• The best corrected visual acuity for far distance, close-up visus and average retinal sensitivity increased in both groups.
• Patient compliance analysis showed that 6 months after surgery, 52.78% of patients recorded better vision, 38.89% no change and 8.33% worsening.
• Significant improved was observed in the group with higher RTA (group B).
• Cell therapy by autologous cell graft in the suprachoroidal space seems to afford a functional improvement in retinal residual cells, proportional to their condition, with positive consequences on patient visual performance. Including in severe cases the contribution of GFs to the residual cells of the retina allows the optimization of rehabilitation and recovery of lost capacity with appropriate magnifying systems.
• No adverse effects were reported in any case and mean values of the intraocular pressure recorded before and after surgery did not change significantly.

Ronci et al
Transfus Apher Sci 2015

RegenKit

• All patients improved their clinical condition during follow-up, all epithelial defects healed or improved starting from the 2nd week of treatment, as demonstrated by fluorescein staining, photograph and disappearance of symptoms.
• In patients with severe dry eye (SDE), best corrected visual a fluorescein staining improved only during the PRP eye drop treatment.
• Topical instillation of autologous PRP was effective in healing ocular epithelial defects. High level of platelet counts seems not required to treat corneal lesions.
• No adverse events related to PRP treatment were reported during the follow-up visits.

Victor et al
Acta Ophthalmologica 2018

RegenKit

• Significantly larger reduction in symptomatology (p < 0.001), visual improvement (p < 0.001), reduction in hyperaemia (p < 0.001), and corneal and conjunctival staining (p < 0.001), increment of Schirmer test outcome (p ≤ 0.005), and reduction of osmolarity were found in the PRP group in both eyes compared to SH group at 15 and 30 days of treatment.
• A significantly higher increment of caliciform cell density (p < 0.001) was found in the PRP group. Strong and statistically significant correlations were found in the PRP group of the change achieved in visual acuity, hyperaemia, osmolarity, and conjunctival and corneal staining with the baseline values of these variables (p < 0.001).
• In contrast, these moderate and strong correlations were not found in the SH group which suggests that PRP may be a better option of treatment in those eyes with moderate and severe dry eye.