Reference 參考資料 |
Pathology/Product used 病理症狀/使用產品 |
Key results on performance & adverse events 主要治療結果 & 不良反應記錄 |
Trichologic response of platelet-rich plasma in androgenetic alopecia is maintained during combination therapy
Ho et al J Am Acad Dermatol 2020
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Androgenic alopecia
RegenKit
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- A positive response to PRP was seen in 70.8% of patients two months after the initial injections.
- Hair density after PRP treatment showed a statistically significant increase from baseline on the anterior crown (+24.5 hairs/cm?, p=0.022). PRP treatment increased hair density by more than 10% over baseline in 62.5% of patients and by more than 20% over baseline in 33.3% of patients. One patient had an increase in hair density of more than 50%.
- Changes in hair shaft diameter did not reach statistical significance.
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Stratifying clinical response to adjuvant platelet-rich plasma in patients with androgenetic alopecia
Juhasz et al Br J Dermatol 2020
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Androgenic alopecia
RegenKit
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- A positive response to adjuvant PRP was reported in 70.1% of patients after two sessions, with patients showing an increase in hair density to varying extents.
- No significant improvement in hair shaft diameter observed.
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Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study
Kadry et al Clin Cosmet Investig Dermatol 2018
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Vitiligo
RegenKit
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- Both the combined Fr: CO2 with PRP group and PRP group showed the highest significant improvement when compared to other modalities (P<0.001).
- A combination of Fr: CO2 and PRP is more effective than either alone for the treatment of vitiligo.
- Pain was the most common adverse event. Hyperpigmentation occurred in the Fr:C02 (26.66%) and combined Fr:CO2 with PRP groups (6.66%).
- There were also reports of inflammation that developed in the Fr:CO2 group and the combine Fr:CO2 with PRP group. Ecchymosis in the PRP and combined Fr:CO2 with PRP groups lasted for 3-5 days.
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Histologic evidence of new collagen formulation using platelet rich plasma in skin rejuvenation: a prospective controlled clinical study
Abuaf et al Ann Dermatol 2016
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Skin aging
RegenKit
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- Objective histopathological examination of biopsy samples showed an increase in the number and thickness of elastic fibers and collagen content with both saline and PRP (p<0.001).
- The improvement in the PRP-treated side compared to the saline placebo- treated side was statistically highly significant (p<0.001). In fact, the improvement on the saline side was 46.01% vs. 89.05% on the PRP side.
- No serious side effects reported.
- Mild and transient side effects such as bruising or ecchymosis, burning sensation, mild erythema, and severe erythema were observed.
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Initial experience of face augmentation using fat graft-platelet rich plasma mix
Tolba et al Surg Sci 2015
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Facial augmentation
RegenKit
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- The results were evaluated by the patient and surgeon comparing pre-and post-operative images for the degree of improvement.
- 70% of the patients were assessed as excellent, 20% were satisfactory and 10% were unsatisfactory.
- Bruising of the treated area occurred in 15 patients. Redness and swelling occurred in 3 patients. All issues resolved within an average of 4 days after the procedure.
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Regression of melisma with platelet-rich plasma treatment
Cayirli et al Ann Dermatol 2014
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Melasma for 5 years
RegenKit
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- At the end of the third session, >80% reduction in epidermal hyperpigmentation was observed.
- No additional treatments or post treatment care (besides the use of a sunscreen) were prescribed.
- No melasma recurrence during the 6- month follow-up.
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