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Reference
參考資料
Pathology/Product used
病理症狀/使用產品
Key results on performance & adverse events
主要治療結果 & 不良反應記錄
Trichologic response of platelet-rich plasma in androgenetic alopecia is maintained during combination therapy

Ho et al
J Am Acad Dermatol 2020

Androgenic alopecia

RegenKit

  • A positive response to PRP was seen in 70.8% of patients two months after the initial injections.
  • Hair density after PRP treatment showed a statistically significant increase from baseline on the anterior crown (+24.5 hairs/cm?, p=0.022). PRP treatment increased hair density by more than 10% over baseline in 62.5% of patients and by more than 20% over baseline in 33.3% of patients. One patient had an increase in hair density of more than 50%.
  • Changes in hair shaft diameter did not reach statistical significance.
Stratifying clinical response to adjuvant platelet-rich plasma in patients with androgenetic alopecia

Juhasz et al
Br J Dermatol 2020

Androgenic alopecia

RegenKit

  • A positive response to adjuvant PRP was reported in 70.1% of patients after two sessions, with patients showing an increase in hair density to varying extents.
  • No significant improvement in hair shaft diameter observed.
Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study

Kadry et al
Clin Cosmet Investig Dermatol 2018

Vitiligo

RegenKit

  • Both the combined Fr: CO2 with PRP group and PRP group showed the highest significant improvement when compared to other modalities (P<0.001).
  • A combination of Fr: CO2 and PRP is more effective than either alone for the treatment of vitiligo.
  • Pain was the most common adverse event. Hyperpigmentation occurred in the Fr:C02 (26.66%) and combined Fr:CO2 with PRP groups (6.66%).
  • There were also reports of inflammation that developed in the Fr:CO2 group and the combine Fr:CO2 with PRP group. Ecchymosis in the PRP and combined Fr:CO2 with PRP groups lasted for 3-5 days.
Histologic evidence of new collagen formulation using platelet rich plasma in skin rejuvenation: a prospective controlled clinical study

Abuaf et al
Ann Dermatol 2016

Skin aging

RegenKit

  • Objective histopathological examination of biopsy samples showed an increase in the number and thickness of elastic fibers and collagen content with both saline and PRP (p<0.001).
  • The improvement in the PRP-treated side compared to the saline placebo- treated side was statistically highly significant (p<0.001). In fact, the improvement on the saline side was 46.01% vs. 89.05% on the PRP side.
  • No serious side effects reported.
  • Mild and transient side effects such as bruising or ecchymosis, burning sensation, mild erythema, and severe erythema were observed.
Initial experience of face augmentation using fat graft-platelet rich plasma mix

Tolba et al
Surg Sci 2015

Facial augmentation

RegenKit

  • The results were evaluated by the patient and surgeon comparing pre-and post-operative images for the degree of improvement.
  • 70% of the patients were assessed as excellent, 20% were satisfactory and 10% were unsatisfactory.
  • Bruising of the treated area occurred in 15 patients. Redness and swelling occurred in 3 patients. All issues resolved within an average of 4 days after the procedure.
Regression of melisma with platelet-rich plasma treatment

Cayirli et al
Ann Dermatol 2014

Melasma for 5 years

RegenKit

  • At the end of the third session, >80% reduction in epidermal hyperpigmentation was observed.
  • No additional treatments or post treatment care (besides the use of a sunscreen) were prescribed.
  • No melasma recurrence during the 6- month follow-up.
以上期刊文獻僅提供專業人士參考,產品之臨床使用範圍應依據衛福部核准中文仿單之適應症為宜。